I did a test using line and brush. I am comfortable with both, I just need your opinion.
http://www.filz.us/tFS

It's not about the tool, it's about the animator.

^ True dat.

Uh, to be honest you need a lot more practice, practice more and more and more, and more, and a little bit more and then you'll be a decent twat.

It really depends on who you are, and how you animate.

Depends on your style. Some animators use the Brush, some use line, some use pencil, some use all of them. You just have to animate more to find a tool that suits your style.